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  • Scenario III: Mutations
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The Story

If the opsin protein is incorrectly formed in an individual, that could lead to the inability to absorb light in the red spectrum of wavelengths.  If we have the DNA sequence of multiple individuals, can we identify from the DNA sequence which individual will have the incorrectly formed opsin protein? 

The solution lies in identifying single nucleotide changes, also known as single nucleotide polymorphisms (SNPs) in our sequence with respect to the reference. But remember that not all single nucleotide changes will affect the protein and have deleterious effects.

Molecular Biology Concepts

 

 

Mutations: A primer

 

Programming concepts

Python regular expressions

Problem sets

 

  1. Additional Resources

 

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