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We know that the OPN1LW gene is associated with colorblindness. While this gene is present in all humans, colorblindness affects only a few. What is different about the gene in those affected by colorblindness? Perhaps the answer lies in the level of expression of the OPN1LW gene. A gene's expression is regulated by various elements in the human body. Let's see if we can bioinformatically identify the regulatory elements of our gene of interest.
Molecular Biology
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concepts
StStructures and Motifsmotifs
Programming concepts
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Problem sets
- Scan the genome upstream of the sequence looking for sequences that match criteria for regulatory sequence.
Find motifs in our sequence and compare them to motif databases.
Files required:
OPN1LW_nuclsequence.hg19upstream20000.fastaOPN1LW_annotation.hg19.gtf
Additional Resources