Overall Course Learning Objectives

  • Be capable of navigating a Linux operating system and TACC's Lonestar system in particular
  • Understand the biological questions, technologies, and workflows related to genome variant analysis, including:
    • Types of variants detectable by NGS
    • Terms: eQTL / GWAS / causative mutation analysis / population genetics
    • phylogenetics: evolution (e.g. quasi-species evolution), ecology (e.g. populations, pooled samples, bacterial communities)
    • Genotype / phenotype associations - either at a gross scale (e.g. mapping) or fine scale (e.g. causative mutations)
    • Technologies:
      • WGA
      • Exome
      • ddRAD
      • sequencing technologies
  • Related topics which are outside the scope of this course include: allele specific expression, methylation analysis, ChIP-seq, RIP-seq

Learning Objectives: Day 1, Part 1: Linux/TACC Introduction

  • Learn and practice essential Linux concepts and commands, including where to get more help & information
  • Learn and practice working with TACC systems (Lonestar in particular)

Other Resources:

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